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نانو کپسوله سازی ، یک رویکرد ِ امید بخش در تحویل هدفمند و آزاد سازی کنترل شده ء ویتامین ها

عنوان انگلیسی: Nano-encapsulation as a promising approach for targeted delivery and controlled release of vitamins
سال نشر: ۲۰۱۶
نویسنده: Iman Katouzian , Seid Mahdi Jafari
رشته های مرتبط: پزشکی
تعداد صفحه فارسی: ۳۳- تعداد صفحه انگلیسی: ۱۵
شناسه: ۱۰.۱۰۱۶/j.tifs.2016.05.002
دانشگاه: University of Agricultural Science and Natural
نشریه: Trends in Food Science & Technology


 ویتامین ها مولکولهای زیست فعالی هستند که برای سلامت انسان ضروری بوده و بسیار تجزیه پذیرند . در حین ترکیب ، قابلیت زیستی این ترکیبات ممکن است به خاطر ساختار شکننده و جذب پایین محدود شود . امروزه نانوکپسوله سازی می تواند رویکردی امید بخش و مناسب برای تحویل ویتامین های هدف و محافظت از این ترکیبات زیست فعال در برابر شرایط محیطی مخرب در حین فرآیند و تحویل باشد . نانوکپسوله سازی در بخش غذایی و نوشیدنی ها مزایای بی شماری دارد لذا به جنبه ء ایمنی بیشتر این حامل های کوچک باید به تعمیم بیشتر این روش نیز پرداخت . بخاطر اثرات منفی محتمل ِ این ریز مواد ، برخی از نهادها قوانین سیاسی ای را برای اجتناب از ضررات بالقوه ء این مواد برای مشتریان بنانهاده اند که در این مقاله به آنها می پردازیم .


Vitamins are bioactive molecules necessary for human health, which are sensible to degradation. During consumption, the bioavailability of these compounds might be limited due to structure break-down and low absorption. Today, nanoencapsulation can be a promising approach for targeted delivery of vitamins and protecting these bioactive components against destructive environment during processing and delivery. Regarding the benefits of utilizing nanotechnology in the food sector, safety aspects of these tiny carriers should also be clarified as this technology develops. Due to the possible negative effects of nanomaterials, several agencies have legislated regulatory policies to prevent potential harms to the consumers, which are underlined in this article.

Scope and approach
Nanoencapsulation-based technologies are a unique and novel field of investigation in the food and pharmaceutical industry with benefits, such as higher bioavailability, high shelf-stability and controlled release of active compounds. This review highlights recent works on these techniques and advances made in nanoencapsulation of lipophilic and hydrophilic vitamins, safety issues and health risks regarding the consumption of these products, which opens new horizons in food technology and nutrition with possibilities of commercialization in the near future.

Key findings and conclusions
Recently, considerable progresses are being carried out in the field of food nanoencapsulation involving novel nanovehicles to encapsulate vitamins. Nanofibers and nanohydrogels are some examples of efficient and modern nanocarriers. Overall, the vitamins encapsulated within nanovehicles are considered safe since they are mostly produced from food components, meanwhile more studies should be performed regarding the safety issues of nanodelivery of vitamins. In near future, it is assumed that nanoencapsulated vitamins will be broadly applied the in the food and beverage products.

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